Table 4

Serum Clinical Chemistry Markers

300 mg
 600 mg
Week
 0
 1
 3
 8
 11
 0
 1
 3
 8
 11
Triglyceride (mg/dl)
 86.8 ± 29.5
 98.5 ± 46.1
 105.3 ± 29.5
 110.3 ± 58.8
 85.9 ± 41.9
 117.5 ± 60.2
 115.5 ± 50.5
 116.6 ± 40.5
 110.9 ± 43.4
 97.8 ± 36.1
Cholesterol (mg/dl)
 177.0 ± 38.2
 182.1 ± 26.1
 173.9 ± 32.2
 175.0 ± 22.6
 166.1 ± 20.7
 194.6 ± 24.9*
 185.1 ± 22.3*
 201.1 ± 20.8*
 201.6 ± 37.8*
 199.5 ± 31.0*
HDL (mg/dL)
 50.1 ± 12.5
 51.3 ± 10.9
 53.6 ± 17.6
 49.4 ± 7.9
 48.3 ± 8.9
 53.0 ± 4.7
 53.8 ± 9.8
 58.5 ± 11.9
 53.9 ± 18.7
 57.0 ± 18.3
LDL (mg/dL)
 107.9 ± 26.9
 112.0 ± 18.8
 105.4 ± 23.5
 104.4 ± 22.8
 100.6 ± 16.8
 115.9 ± 21.5*
 111.4 ± 21.7*
 124.8 ± 22.0*
 127.1 ± 33.5*
 121.4 ± 25.2*
GGT (U/L)
 23.9 ± 5.7
 23.8 ± 4.6
 23.1 ± 4.8
 27.3 ± 7.9
 26.0 ± 7.0
 32.3 ± 9.6*
 33.6 ± 11.2*
 33.6 ± 7.8*
 38.8 ± 11.8*
 36.4 ± 8.3*
LDH (U/L)
 127.0 ± 19.4
 130.6 ± 23.3
 125.4 ± 19.6
 114.5 ± 25.8
 130.0 ± 33.0
 125.5 ± 17.4
 128.0 ± 18.0
 132.8 ± 23.4
 132.1 ± 24.6
 140.6 ± 32.6
Uric Acid (g/dl)
 6.1 ± 1.7
 5.8 ± 1.1
 5.7 ± 0.9
 5.2 ± 1.0
 5.5 ± 1.4
 6.1 ± 1.3
 6.1 ± 1.6
 6.5 ± 1.2
 5.7 ± 1.0
 5.7 ± 1.3
Glucose mg/dl
 94.5 ± 9.4
 95.8 ± 10.3
 97.6 ± 10.4
 94.0 ± 8.2
 93.9 ± 9.6
 95.1 ± 8.4
 94.3 ± 6.5
 100.5 ± 6.1
 105.1 ± 17.1
 89.9 ± 14.8
BUN (mg/dL)
 16.9 ± 2.9
 19.4 ± 5.0
 20.6 ± 4.5
 18.5 ± 3.0
 19.4 ± 3.6
 21.1 ± 7.6*
 22.3 ± 5.1*
 22.5 ± 3.8*
 19.8 ± 3.5*
 21.3 ± 2.4*
Creatinine (mg/dl)
 1.4 ± 0.1
 1.4 ± 0.2
 1.4 ± 0.2
 1.3 ± 0.2
 1.3 ± 0.3
 1.4 ± 0.2
 1.4 ± 0.2
 1.5 ± 0.2
 1.5 ± 0.2
 1.3 ± 0.3
Calcium (mg/dl)
 12.5 ± 1.7
 14.2 ± 3.2
 14.8 ± 3.0
 14.9 ± 2.1
 15.2 ± 3.4
 15.6 ± 4.4*
 16.4 ± 3.4*
 14.9 ± 2.8*
 13.7 ± 2.6*
 17.0 ± 3.0*
Total Protein g/dL
 9.8 ± 0.5
 9.9 ± 0.4
 9.9 ± 0.6
 9.8 ± 0.5
 9.5 ± 0.4
 10.1 ± 0.6*
 10.1 ± 0.7*
 10.8 ± 0.7*
 10.4 ± 0.7*
 10.2 ± 0.9*
Albumin g/dL
 7.4 ± 0.6
 7.7 ± 0.4
 7.8 ± 0.6
 7.4 ± 0.5
 7.3 ± 0.5
 7.9 ± 0.9*
 8.0 ± 0.9*
 8.5 ± 1.0*
 8.3 ± 0.9*
 8.1 ± 0.9*
Total Bilirubin (mg/dl)
 4.7 ± 0.5
 4.8 ± 0.4
 4.9 ± 0.5
 4.6 ± 0.5
 4.6 ± 0.3
 5.0 ± 0.5
 5.1 ± 0.5
 5.4 ± 0.6
 5.3 ± 0.6
 5.1 ± 0.6
ALP (U/L)
 0.8 ± 0.3
 0.8 ± 0.6
 1.0 ± 0.4
 0.9 ± 0.5
 0.9 ± 0.6
 0.6 ± 0.3
 0.6 ± 0.2
 0.9 ± 0.4
 0.8 ± 0.3
 0.8 ± 0.2
AST (U/L)
 73.9 ± 13.3
 76.3 ± 12.1
 73.1 ± 12.8
 70.5 ± 15.7
 64.0 ± 19.9
 77.1 ± 21.3
 76.1 ± 21.0
 79.5 ± 19.4
 76.4 ± 19.0
 63.1 ± 27.8
ALT (U/L)
 24.4 ± 9.6
 24.5 ± 9.3
 21.3 ± 6.8
 18.3 ± 6.6
 30.3 ± 25.1
 22.6 ± 6.5
 27.3 ± 5.5
 30.0 ± 11.7
 24.5 ± 8.0
 26.3 ± 10.0
CK (U/L)
 28.6 ± 11.5
 25.6 ± 5.5
 22.4 ± 7.2
 28.4 ± 10.8
 27.1 ± 5.5
 28.1 ± 14.2
 25.0 ± 7.2
 23.8 ± 6.7
 28.9 ± 15.6
 32.6 ± 10.7

* Denotes significant main effects for groups (p < 0.05) indicating that the 600 mg group had higher baselines that persisted throughout the study, and was apparently independent of 6-OXO supplementation.

Rohle et al. Journal of the International Society of Sports Nutrition 2007 4:13   doi:10.1186/1550-2783-4-13